منابع مشابه
Interleukin-32 in Inflammatory Autoimmune Diseases
Interleukin-32 (IL-32) is a cytokine inducing crucial inflammatory cytokines such as tumor necrosis factor-α (TNFα) and IL-6 and its expression is elevated in various inflammatory autoimmune diseases, certain cancers, as well as viral infections. IL-32 gene was first cloned from activated T cells, however IL-32 expression was also found in other immune cells and non-immune cells. IL-32 gene was...
متن کاملCommensal Microbes: The Frenemy Within
As part of their symbiotic association with humans, intestinal bacteria sometimes need and sometimes lend a helping hand. In this Select, we examine how commensal microorganisms or the inflammation they produce cause undesirable outcomes, such as the development of type 2 diabetes or cancer. In addition, we see how commensal bacteria can receive assistance in colonization from resident phages a...
متن کاملHuman Cancer Biology Interleukin-32 IncreasesHumanGastric Cancer Cell Invasion Associated with Tumor Progression and Metastasis
Purpose: The proinflammatory cytokine interleukin-32 (IL-32) is a novel tumormarker highly expressed in various human carcinomas, including gastric cancer. However, its effects on prognosis of patients with gastric cancer and cancer metastasis are virtually unknown at present. The main aim of this study was to explore the clinical significance of IL-32 in gastric cancer and further elucidate th...
متن کاملInterleukin-32 increases human gastric cancer cell invasion associated with tumor progression and metastasis.
PURPOSE The proinflammatory cytokine interleukin-32 (IL-32) is a novel tumor marker highly expressed in various human carcinomas, including gastric cancer. However, its effects on prognosis of patients with gastric cancer and cancer metastasis are virtually unknown at present. The main aim of this study was to explore the clinical significance of IL-32 in gastric cancer and further elucidate th...
متن کاملInterleukin-32 Promotes Osteoclast Differentiation but Not Osteoclast Activation
BACKGROUND Interleukin-32 (IL-32) is a newly described cytokine produced after stimulation by IL-2 or IL-18 and IFN-gamma. IL-32 has the typical properties of a pro-inflammatory mediator and although its role in rheumatoid arthritis has been recently reported its effect on the osteoclastogenesis process remains unclear. METHODOLOGY/PRINCIPAL FINDINGS In the present study, we have shown that I...
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ژورنال
عنوان ژورنال: BMB Reports
سال: 2019
ISSN: 1976-670X
DOI: 10.5483/bmbrep.2019.52.3.019